3D printed bioengineered scaffold containing chitosan, alginate, and Barijeh-loaded niosomes enabled efficient antibiofilm activity and wound healing.

Summary: Imagine a smart bandage that not only covers a wound but actively fights off bad bacteria and helps the skin heal faster. Scientists have created exactly that using 3D printing! They mixed natural ingredients like chitosan and seaweed extract with a special plant medicine called Barijeh. To make the plant medicine work better, they packed it into tiny bubbles called niosomes. When tested on mice, this 3D-printed patch killed harmful bacteria, stopped them from grouping together, and healed over 90% of the wound in just 10 days. It also lowered swelling and helped the skin rebuild itself safely. This could be a game-changer for treating nasty cuts and infections!