A Case Report on the Development of Ulcerative Colitis During Osimertinib Therapy for Epidermal Growth Factor Receptor Mutation-Positive Non-Small-Cell Lung Cancer.

Summary: Imagine taking a daily pill to fight lung cancer, but suddenly you get severe, non-stop stomach issues. That is exactly what happened to a 69-year-old woman. She was taking a cancer medicine called osimertinib and developed terrible diarrhea that wouldn't go away, even after her doctors told her to stop taking the pill. Her doctors decided to look inside her colon with a special camera and found she had developed a painful bowel disease called ulcerative colitis. The good news? Once they gave her a specific medicine for the colitis, her stomach problems finally stopped. This story helps doctors know what to look for if cancer patients get severe diarrhea from their treatments.