Bussuquara Virus: A Neglected Orthoflavivirus with Broad Distribution Across Central and South America and the Caribbean.

Summary: Deep in the rainforests of the Amazon, a virus known as Bussuquara (BSQV) has been circulating quietly since its discovery in 1956. While it primarily affects rodents and is spread by mosquitoes, it is a close relative of more famous viruses like Dengue and Yellow Fever. Although it rarely makes humans sick—causing only mild fever when it does—scientists have found that it has spread far beyond Brazil into Central America and the Caribbean. Because it is so widespread, researchers urge that we shouldn't ignore it; monitoring this "neglected" virus is essential to ensure it doesn't become a future public health threat.