Cellular neighborhoods inside tumors may predict which patients with melanoma benefit from combination immunotherapy

Summary: Doctors at UCLA found a new way to tell if a skin cancer (melanoma) treatment will work. Instead of just looking at genes, they look at how cells are grouped inside the tumor, calling them "cellular neighborhoods." If cancer-killing T-cells are close to the cancer, the treatment usually works. But if there are too many plasma cells blocking the way, the treatment often fails. This discovery helps doctors pick the best medicine for patients faster.

For more details, see rssapp-uclahealth-org-news at uclahealth.org/news/release/cellular-neighborhoods-inside-tumors-may-predict-which (opens in new tab)

Tags

Neoplasms
Melanoma
Nivolumab
Ipilimumab