CXCR6 defines a distinct resident state in γδ T cells for protecting from liver cirrhosis.

Summary: Liver cirrhosis is a dangerous disease that causes severe scarring in the liver. Scientists have found a special group of immune cells, called T cells, that live in the liver and act like tiny guards. In a healthy liver, these guards are plentiful and help stop scarring by clearing away bad cells. But in a sick, scarred liver, these helpful guards are missing. When researchers gave these special T cells to mice with liver scarring, their livers got much better! This exciting discovery means we might one day use these immune cells as a new treatment to heal liver disease in humans.