Effect of the GLP-1 receptor agonist exenatide on pro-inflammatory and metabolic biomarkers in individuals with alcohol use disorder: Post hoc results from a randomized, double-blinded, placebo-controlled clinical trial.

Summary: People with alcohol use disorder (AUD) often have more swelling and stress inside their bodies. Scientists wanted to see if a diabetes drug called exenatide could help calm this down. First, they checked the blood of people with and without AUD. They found that people with AUD did have more signs of swelling. Next, they gave some people with AUD the drug exenatide for 26 weeks, while others got a fake shot (placebo). The result? The drug did not change the signs of swelling or stress in the blood. So, while alcohol does cause swelling, this specific drug didn't fix it.