Effects of Empagliflozin on Urine Biomarkers in EMPA-KIDNEY.

Summary: "Flozins" are special medicines that protect the kidneys, but doctors aren't exactly sure how they work. In a large study with over 2,700 patients, researchers tested a flozin called empagliflozin. They found it greatly lowered the amount of two proteins in the urine: albumin and uromodulin. The big drop in uromodulin was a surprise! This protein is made in a different part of the kidney than where the medicine normally works. This new discovery might be the secret to how these drugs keep kidneys healthy.