Evaluation of the quality of the fixed-dose triple combination dispersible tablet for HIV-positive paediatric population after the continuous direct compression and batch manufacturing techniques.

Summary: Children with HIV often have a hard time taking their medicine. Liquid medicines can go bad quickly, and powders can be tricky to mix with food. To fix this, scientists tried making a new kind of tablet that dissolves in water. It combines three different HIV drugs into one single pill. They tested two different ways to make these tablets in a factory to see which was better: a continuous method and a batch method.

The good news? Both ways worked well and made similar, high-quality tablets! Two of the drugs dissolved perfectly in water, but one drug was a bit stubborn and needs more work to mix properly. Overall, this is a big step toward making safer, easier-to-take medicines for kids.

Tags

Zidovudine
Powders
Tenofovir
Fumarates
Bulk Drugs
Dosage Forms
Pharmacopoeia