Exploring the role of β2- and β3-adrenergic receptors in cystic fibrosis.

Summary: Cystic fibrosis (CF) is a disease passed down through families that makes thick, sticky mucus build up in the lungs and other organs. This happens because a tiny part of the body's cells, called CFTR, doesn't work right. Scientists are looking at other parts of the cells, called beta receptors, to see how they can help. Beta-2 receptors help open up the airways and are already targeted by inhaler medicines used today. Now, researchers are finding that Beta-3 receptors also help clear the lungs by making tiny hairs sweep better. Targeting these Beta-3 receptors could be a great new way to help people with CF breathe easier and live healthier lives.