Gene expressions of clinical Pseudomonas aeruginosa harboring RND efflux pumps on chromosome and involving a novel integron on a plasmid.

Summary: Imagine a superbug that can fight off almost every medicine we try to use against it. Scientists recently studied a specific germ, called Pseudomonas aeruginosa XM8, that does exactly this. It acts like a tiny, heavily armed fortress. First, it has special "pumps" that spit antibiotics out before they can work. Second, it shuts down the "doors" that medicines usually use to get inside. Finally, it carries a brand-new piece of DNA, called In4881, which it can easily share with other germs to make them strong, too. Right now, only one powerful drug called colistin can stop it. Doctors and scientists need to be very careful to stop this germ from spreading!