High-throughput screening of human genetic variants by pooled prime editing.

Summary: Scientists have a cool new way to study human DNA changes! Usually, it is hard to test many DNA changes at once inside living cells. Now, researchers have created a new "prime editing" tool that acts like a tiny, super-accurate word processor for DNA. They used it to test thousands of DNA changes in a lab dish to see which ones cause disease. This new tool is highly accurate and will help doctors understand exactly what causes different human diseases.

Tags

High-Throughput Screening Assays
Thioguanine