Injection allergen immunotherapy for asthma.

Summary: For years, doctors have debated whether allergy shots (immunotherapy) are a safe and effective way to treat asthma. A major review of 88 clinical trials has provided a clearer answer: yes, they work. The treatment significantly reduces asthma symptoms and cuts down the need for daily medication. In fact, for every three patients treated, one avoids a worsening of symptoms. However, this relief comes with risks. Because the shots contain allergens, they can trigger reactions. About one in nine patients may experience a systemic reaction (affecting the whole body), and injection sites often become sore. While the benefits can be comparable to inhaled steroids, patients must weigh the symptom relief against the risk of adverse reactions.