Liver regeneration in surgical animal models - a historical perspective and clinical implications.

Summary: Your liver is the only organ that can grow back after being cut, a "superpower" doctors have studied in animals since 1877. Despite modern surgical advances, some patients still suffer liver failure because their liver doesn't regenerate fast enough. This review highlights that while mice are often used in labs, research on larger animals like pigs and dogs gives us a much better picture of how human bodies heal. The authors conclude that to save more lives, liver surgeons and lab scientists must work together closely, using these large animal studies to develop better treatments.