Localized treatment of glioblastoma: a review of clinical strategies and advances in drug delivery systems.

Summary: Glioblastoma is a very tough brain cancer to treat. Even with surgery and strong medicines, patients still struggle to get better. But scientists are working on a new, hopeful idea: putting the medicine exactly where the tumor is, instead of treating the whole body. This review looks at new ways to deliver drugs right into the brain, either during surgery or using special tools. These new delivery systems could make treatments work much better and give patients more hope for the future.