Molecular Hydrogen Therapy Enhances Immune Markers in Treg, Plasma, Tr1 Cells, and KLRG1 Expression on Tc Cells: A Case of Acute SDH With Midline Shift and Uncal Herniation Post-decompressive Craniectomy.

Summary: A 24-year-old man suffered a life-threatening brain bleed (subdural hematoma) caused by trauma, which put severe pressure on his brain. Doctors performed emergency surgery to remove part of the skull and used advanced treatments like hyperbaric oxygen and stem cell therapy to stabilize him. As a novel addition to his care, they administered molecular hydrogen capsules daily. While the surgery and standard care did the heavy lifting for his survival, the hydrogen therapy appeared to safely boost specific "peacekeeping" immune cells (Tregs) and plasma cells without any side effects. This case suggests hydrogen could be a helpful, safe add-on for treating severe brain injuries.