NDM-5-carried outer membrane vesicles impair the efficacy of antibiotics against bacterial infections.

Summary: Farmers use a lot of antibiotics to keep farm animals healthy. But this has caused a big problem: "superbugs" that medicine can't kill. This study looks at a sneaky trick these bacteria use to survive. They send out tiny bubbles (called vesicles) carrying a special shield called NDM-5. This shield breaks down our antibiotic medicines before they can even reach and kill the bacteria. Because of these tiny bubbles, the antibiotics stop working, making bacterial infections much harder to treat.