Pharmacogenomic of LH and its receptor: are we ready for clinical practice?

Summary: Imagine if fertility treatments could be tailored specifically to your unique DNA. Luteinizing Hormone (LH) is a crucial hormone for reproduction and is often used as a drug to help women conceive during assisted reproduction. However, not every woman responds to this drug in the same way; much of this difference lies in her genes. Scientists are exploring "pharmacogenomics"—matching drug treatments to genetic profiles—to make ovarian stimulation safer and more effective, specifically for conditions like Polycystic Ovarian Syndrome (PCOS). While the science is exciting and holds great promise for personalized medicine, we still lack enough large-scale clinical studies to make this a standard practice for everyone just yet.