Protocol to screen chemicals to enhance homology-directed repair in CRISPR-Cas9 gene editing.

Summary: Scientists use a tool called CRISPR to edit genes, much like using molecular scissors to fix typos in our DNA. However, cells sometimes make mistakes when trying to glue the cut DNA back together. To solve this, researchers created a step-by-step guide to test thousands of chemicals at the exact same time. They want to find special chemicals that help the cells repair the DNA perfectly. This new testing guide will help scientists discover better ways to edit genes safely and accurately.