Selection of stable reference genes for qPCR-based analysis of circulating cell-free DNA levels in peripheral blood of neuroblastoma patients.

Summary: Neuroblastoma is a complex childhood cancer. Doctors can look for clues about the cancer by testing tiny pieces of DNA floating in a patient's blood. To make sure these blood tests are accurate, scientists need a reliable "ruler" or baseline to measure against. This study tested different genes to find the best and most stable ones to use as this baseline. Finding the right baseline helps doctors accurately compare sick kids with healthy kids and track the disease better.