Seminal Vesicle Involvement of Waldenström Macroglobulinemia on 18 F-FDG PET/CT.

Summary: A 57-year-old man went to the hospital complaining of persistent lower abdominal pain that had lasted for over two weeks. Initial standard scans (CT and MRI) showed suspicious masses in his seminal vesicles and prostate, looking very much like typical tumors. Doctors ordered a specialized PET scan, which lit up these areas, confirming high metabolic activity. However, the final answer came from a biopsy: it wasn't prostate cancer or a standard gland tumor. It was Waldenström Macroglobulinemia, a rare type of blood cancer, which had unusually invaded the seminal vesicles. This case highlights how advanced imaging and biopsy are crucial for identifying rare disease locations.