Strategies for the prevention of central venous catheter infections: an American Pediatric Surgical Association Outcomes and Clinical Trials Committee systematic review.

Summary: Central venous catheters (CVCs) are vital tubes used to give medicine to sick children, but they carry a high risk of serious bloodstream infections. Doctors reviewed 20 years of medical research to find the best ways to keep these children safe. The study confirmed that three specific strategies work best: cleaning the skin with chlorhexidine before inserting the tube, using special catheters coated with antibiotics or antiseptics, and "locking" the tube with alcohol or antibiotics when not in use. These steps significantly lower the risk of dangerous infections in pediatric patients.