Variable Schwann cell merlin inactivation is targetable with TEAD1 inhibition in schwannomas.

Summary: Imagine your ear nerves have a tiny switch that keeps cells from growing out of control. Sometimes, this switch (called "merlin") breaks, causing small lumps called schwannomas. These lumps can press on nerves, causing hearing loss and brain problems. Scientists have found a new way to stop these lumps from growing by blocking a specific part of the cell called TEAD1. This could be a promising new treatment to help save hearing and stop the tumors!